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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c69c88d94c88f767445d3bde6a436a1f1ac00819fe4f97294ed935a31b46eb64' 
  AND token = 'gbtelSHDMcwFr2jLLPxOYXQVu+sr6HwpBNYyQdb4Aos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}