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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed12d9105c3bbfa0dbdb73c2d770ec30b8899a840e53f0984250f02c5125f832' 
  AND token = 'LQQ8TgyLdP40nW/DXYL/LkR0Yd9kofVyDjz72IuXBzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}