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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6173ba8cceeee365cf907cdd138f59c4a608eb519cce82cf13d0983043750e8' 
  AND token = 'nv1KBNGrapAotxlx8zM5JVAq+XBkT2K/v0c4UfkDZ+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}