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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '885ef323f3fbef1793eca44ba6d762c1c81411557b6f0d01f2244c1644e47098' 
  AND token = 'gNDv/TAJvnu6e35/LvVZfXAmis5ZNhlcHS4Sy3AIO9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}