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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09f499e4b2b26600c4541612bfbc3b09e1ff224127db51d6675954ebc2e3d19e' 
  AND token = 'Puwg1Zv1znXZTct/xCvs/euOb8+39rzAcaDDSfpxRs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}