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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '105212ecf99d9ebdbf5f3837788239c80619738431bd8c48e180d62adebe3e24' 
  AND token = 'OLW4WgoG8Rrg0mg78q2KTaCHNoDGks7cgLoG24+FRKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}