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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1dd1d8a511921e96f5ab620032eff2bddd1708ffd8d910948a2e1c123aeb8b01' 
  AND token = 'o2iYoeZ3rRcChOQ3xqFNYnpXZkSYpyYyYyWwhGME7R4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}