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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4053ef5401e8eb88e713fe171bd47c4b5ea69c1b0d98cd914104d9e94040f5c6' 
  AND token = 'ywYp7nEy0q7CSj9OMVFTeEbjWMbqLWyeLYnoFjRsG28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}