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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fad5d20e746b971455b4388c2df8c0e75d963c3a486b9863c9d4951d5c6e351f' 
  AND token = 'uPt86uRc2RkJqBLvxNlGAUyxtnTTg3i/XpAtArGojSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}