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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '133be455a92c038a4a8d895bd9f0f7e0aca3d054de6b687a2461bbbce0096c97' 
  AND token = 'VXPYOTSKxPIEgxAy9Xl60p7IvZkPcfzN/EF8tAlwG4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}