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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '425712f0d50d3d6ce1abfc47251e8f42bd01bfb23fd96131ebf259702693bae5' 
  AND token = 'yZVJaC1pW+Yey55BqG0dKqfarihCzTrSxqAn2Voqg9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}