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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb52519c4abf2473db1ffa402534e221bf9e239f6cd647edb20d13a4122b0850' 
  AND token = 'O68zAoFAk9Aqdqi+CKgdm25W5qFiqvAp9w0atZSTedQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}