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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed4be601d0eb2bfcb1b1be217a767b7d8d035dfde6e65107362359472a78bce7' 
  AND token = 'W8yKJneO+SCoQ3f7JABRhzaf3CyEXk/RnXcoMx0Ckak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}