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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '880173e7143ded60e10ce083492a4f0a0b0cf5b0c3c065a27b2cbe6c14c7fa41' 
  AND token = 'eXpWBnhgeOLoHmTWmf8qqeA/D3jt4dXRzj+zoDZjruc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}