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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0582910f72449c21233b3d07b9d60f186e5af5d2609067d5bee24d9e5a248716' 
  AND token = 'vJ+opvkfat9yutT6z1ACXgs/lzdR5WbZ37LH4+f8+C4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}