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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e6e618d001e1431994b90228aef907173a58543cd9caf6da49299f350f73a6a' 
  AND token = 'U+YBxLXW54mS1EOd7f1Ujjvalw8MGftcmQx6JTm/On8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}