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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa112efd0ac7009cb209308a0beb26e49fc9f9c9258bb0cc997cb69e82e9355e' 
  AND token = 'iWCTlpDs3X9MeBtQfVG8LhUAWPGhPGUbZTaOGhI4OYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}