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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ce7fd6a241a76bc1d2974493e3cb970e02944ff123a5a8fa52ba273ebc8c260' 
  AND token = '8AOKtgCADEp7/Z6XsGOAXNosCveZ3Wmbt+BuSeX8m4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}