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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4c135ce8d923cb61b60473fd7c6d408982cfe90519e2ac41cfc61228583b6d8' 
  AND token = 'wk2AIR1sI2MLV68lNFR/+evEy7qjFgRTifO9VBfa4IM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}