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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e75209e8c8a388bded2d165dff0e2979dc6f31a3b8941cd12d561301501514d4' 
  AND token = 'kFb45e0VezerBPxd7rDconfeezt6oye4Tjg0BEMD18o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}