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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68e29a3f48127e7a3696552e79bf6831699c902da42ac9664b5fce69ca279545' 
  AND token = 'yMZs3kjf7M5JFlw0iDMQQXdvjcqT2rqh30kmprN8mP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}