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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7aa0b81fa7d7f06135fd2c2c20c137bc740985bf87b0b1e8aaf1ce485fcf1cf3' 
  AND token = 'ap6OZu6S68a4L/boLvtDvRLByZZAAlUjyEbamiRobo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}