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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f22a77c532ccd0e9a2a520fb1b4b2268f31d3a7207aea3a25711ac0005e807c3' 
  AND token = 'iZL173AWAWJ5ySQFDqt+E+X3DPgJJ2hRLKDuoo/h7LI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}