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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4521c4bfa0c9f53e8531c0b1b9322b0d7c187b901e4e8635e5ef3f4104393a51' 
  AND token = 'IxwR1mp1lPqCplhw2itC/K2UC+mpxHsPX6+akphGTEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}