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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '256eb3c1aa03469ebae10662a67747e966f5c3b6bc43e0ec190da27e58b57a6b' 
  AND token = 'qyJQx7BzBnPWFF0tzFAt4XJMhCHcSQZ6rTlfqHtvSpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}