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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '433ca0ed71786354ebfd43423e4b31badffa63eae2ac90fb6c9f25577e03529c' 
  AND token = '0Na1+4GajA6+i7JwV20GxW/c8I1OjJXlme2T3ac02Xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}