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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08d81ccc00453bbeb1b74467f729a3c706f9ce478f8d63f157b58bc38e832754' 
  AND token = '5nuz6AykE8Zfc70bKQAXqGjUQVsqF2spLK9LGEnfwTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}