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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd351b0cacb22c7e2a0af13efecf662a1a3e8cfe905b4122e90eab7855c850588' 
  AND token = 'QsPbKZIpnQsLM69MIsZPB3N9JPsnkBvYM4cZyJgAF0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}