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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c3cdfdf34333bb14549a23a953701b7992181fa78a2d1f867aa107c27b5a225' 
  AND token = 'ha4aOIjlGIKDememT09qVwtZZ2MRvdeTv/Ck9BI58Rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}