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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01e7029d1e4bf3c7573312aa943f856d778cdbcd9235187d2170b6eda9b3b2cd' 
  AND token = 'S/aJe8jLI5mlkPMnWzg29Ffx2+tRlV/6SoZ1XuF/E4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}