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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc1c289d2e4b4dabb34104132cc18b292c37c49e61fe10f0c329f0f9a0bcc141' 
  AND token = 'ylcpOfzeAqBn4sOeaoIsQ7fkfEgUiCghskYG0KOpLiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}