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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b081194ee97e2b78274a675e40648a2b7739c858f1b57071e2233426caedcfec' 
  AND token = 'Mlsxc7Xuf6kgX39zCFbZkzk3EYKUGg5kuv748hKWZVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}