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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f39394c66237cd6bd63ab306fcc936de473c778edd8291dbc1868a19d6b6c66e' 
  AND token = 'x7YXF245Hw0rwWWJ0byreKU0MLlmxyB5cVw7wAbM+dM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}