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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54cb5324738c1d4682e3c7ad32cc7708193d069ab66babfff8920a86a8477d36' 
  AND token = 'kuP/nrGoHd4bSpbeD9KrWdwckpPI+gA1FPqexnzAgXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}