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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c6ff3c756a62d23d141f7556f30b356f113c4eb2d64028bab30c01b081bc5c7' 
  AND token = 'N7EEWmlX0X9VSaSJaTgrh6TaerKGU0wSFjRdLvAmKB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}