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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fb691b5012c2ccfde09bfff47974aecc3df0e23b4fb689766de58ff5f6df558' 
  AND token = 'XWZz+LOCU9ksb2p0ccd6Rhc8AHyZuGls+DdzmLdsMXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}