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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cd7f3538c75c78d7d9bb9ce3322ff34bcdadb53d6bc7745f4914464caa10517' 
  AND token = 'XMlgrdqXrLg1W8Tbdy0LckN5UMTfO3wzro/J2z0xRTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}