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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce6fa86ea1b76852edc6419d25a53d988abf4273bdb66dcedfd9207798aef9f1' 
  AND token = '+nlNtsIbw095GkWYP5MWzx0ny+1iKnkVcaW2Jn7rVrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}