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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '620308b8e1bcdc47d9a28122fffba79c68e3a7eca3a43231c69ed7a223816233' 
  AND token = 'U3d9K2chDoyMHLQ+pk0rPNuHqwdMPEc+CC7ua0/SAqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}