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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67ea53c1db5db7fe468020b4f599dd62b09c672afea3b2d20c8aeca23395a693' 
  AND token = 'VW74Q0DUxfZKM1kB6R538V4oTN87O/P68LCDTDvPsjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}