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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb680f3ecc8babe44dcb0c09a4f72118f7a0ad404ba82e203f007e632fe17655' 
  AND token = 'PPNi7Q6zQ2iAENaH9lQr+m/QkGUmbLlPrm3dA5S/8Zw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}