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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6ffbc8c53c7ca3a8ba70e4ba49f31dc682472144a47d6e20b7c056d7009af34' 
  AND token = '4zOqSqpWNlag7d1RtAjSn+f+l/rkq67EMogr94nvgtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}