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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8abd161c82f1f2f9390545e7236bdf158e34a78849fec9c247edf789baf8994d' 
  AND token = 'jbWuPrPNsJFXNDUP8+4a7uqFd858SNy+xpeXS6UoDk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}