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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afbe41e23579c2e2f3be4e93ba524d6f0bf65c5a61a42baf5821c0597315aaca' 
  AND token = '6FA63ohXnMg/tdw/iPfeYAku45VyLUjCK+XDLxYW3e0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}