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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d445fa3ccadd6893fd92ddfefed6c46d36df77c2ddd04732d9f0184d9ba31fa' 
  AND token = 'SMKAIN0NDt2ozDW/lKO+2+pgxCdjZC+x8gjspU9dHuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}