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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a486ebed8842554b6daff65ba8d4415d78b2501a3b67b14c9adaeaf20bcbad3' 
  AND token = 'qV3I2jQPBkLUxm7S/M363G/TlCJm0v9i3Bgjby6BiQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}