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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd370af0b243ecd08c1d8fa54f718774f49f9ea160e34e77b9bcb188245b827a5' 
  AND token = 'BCG0SUgZ8+VHJnC4pnYEOgHwB3YtqL4E3p8QYZSbx08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}