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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b66882d0c6e2ba01f1079914a93d9468d23abdd3a8a2529586a8849d85e3b04' 
  AND token = '3lA/S7iod8LE1KtISLoN0V/gOdU4BLPFdblSIUAf0IQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}