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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10f583b3b90096cefa8e93c9a5c9c7d853f3168cc2a5d9a9ca9df2fcb14061cb' 
  AND token = 'mkMy+N/Slj5G7gXJkhy1Q61MRnT/mUrBEFoWJtakwcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}