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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca5e5bb866b065a624b8d7f924c07625f00c57e82f793241384502989b2eedfd' 
  AND token = '+qm6LAhu5U8wTrVuvityuiv6kyi9VB69uAuUAZQf374=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}